Omega-3 Fatty Acids EPA and DHA: Health Benefits Throughout Life
Open Access
- 1 January 2012
- journal article
- review article
- Published by Elsevier BV in Advances in Nutrition: An International Review Journal
- Vol. 3 (1), 1-7
- https://doi.org/10.3945/an.111.000893
Abstract
Omega-3 [(n-3)] fatty acids have been linked to healthy aging throughout life. Recently, fish-derived omega-3 fatty acids EPA and DHA have been associated with fetal development, cardiovascular function, and Alzheimer's disease. However, because our bodies do not efficiently produce some omega-3 fatty acids from marine sources, it is necessary to obtain adequate amounts through fish and fish-oil products. Studies have shown that EPA and DHA are important for proper fetal development, including neuronal, retinal, and immune function. EPA and DHA may affect many aspects of cardiovascular function including inflammation, peripheral artery disease, major coronary events, and anticoagulation. EPA and DHA have been linked to promising results in prevention, weight management, and cognitive function in those with very mild Alzheimer's disease.Keywords
This publication has 55 references indexed in Scilit:
- Algal Docosahexaenoic Acid Affects Plasma Lipoprotein Particle Size Distribution in Overweight and Obese AdultsJournal of Nutrition, 2011
- Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysisThe Lancet, 2007
- Omega-3 fatty acids and decidual cell prostaglandin production in response to the inflammatory cytokine IL-1βAmerican Journal of Obstetrics and Gynecology, 2006
- ω-3 Fatty Acid Treatment in 174 Patients With Mild to Moderate Alzheimer Disease: OmegAD StudyArchives of Neurology, 2006
- Compartmental modeling to quantify α-linolenic acid conversion after longer term intake of multiple tracer bolusesJournal of Lipid Research, 2005
- A Diet Enriched with the Omega-3 Fatty Acid Docosahexaenoic Acid Reduces Amyloid Burden in an Aged Alzheimer Mouse ModelJournal of Neuroscience, 2005
- Long-chain conversion of [13C]linoleic acid and α-linolenic acid in response to marked changes in their dietary intake in menJournal of Lipid Research, 2005
- Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case–control studyBritish Journal of Nutrition, 2003
- Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular DiseaseCirculation, 2002
- Fatty acid analysis of blood plasma of patients with alzheimer's disease, other types of dementia, and cognitive impairmentLipids, 2000