SUBJECTIVE AND OBJECTIVE ANALYSIS OF THE PREVALENCE OF PEYRONIE’S DISEASE IN A POPULATION OF MEN PRESENTING FOR PROSTATE CANCER SCREENING
- 1 June 2004
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Urology
- Vol. 171 (6 Part 1), 2350-2353
- https://doi.org/10.1097/01.ju.0000127744.18878.f1
Abstract
Purpose: In this study we defined the prevalence of Peyronie’s disease in a cohort of men being screened for prostate cancer in the United States. The association between Peyronie’s disease, and medical comorbidities and patient self-reported erectile dysfunction was also defined. Materials and Methods: A total of 534 men presenting to 1 of 3 prostate cancer screening centers provided a complete medical history, underwent physical examination performed in all by a urologist and completed the Sexual Health Inventory for Men (SHIM) questionnaire. This population was chosen because of the access to a large number of subjects combined with the fact that subjects were not presenting with a specific urological complaint. The diagnosis of Peyronie’s disease was based on a palpable penile plaque. Data were assessed using univariate analysis, multivariate logistic regression and Pearson chi-square analysis. Results: A total of 48 patients were found to have a palpable penile plaque on physical examination for a prevalence rate of 8.9%. The mean age of men with Peyronie’s disease was 68.2 years compared to a mean of 61.8 years in men without Peyronie’s disease (p <0.0001). On univariate analysis hypertension (p = 0.02) and diabetes (p = 0.007) were present with significantly increased frequency in patients with Peyronie’s disease. Patients diagnosed with Peyronie’s disease had significantly lower values for responses to each of the 5 questions on the SHIM survey. An increase in age and decrease in total SHIM score remained significantly associated with a greater probability of Peyronie’s disease on multivariate analysis. Conclusions: We found the prevalence of Peyronie’s disease to be greater than in most previously reported series. We also noted a significant association between Peyronie’s disease aging, hypertension, diabetes and self-reported erectile dysfunction.Keywords
This publication has 13 references indexed in Scilit:
- The prevalence of Peyronie's disease: results of a large surveyBJU International, 2001
- Is there any association between Peyronie's disease and serum collagen markers?International Journal of Impotence Research, 2000
- A Case-Control Study on Risk Factors for Peyronie’s DiseaseJournal of Clinical Epidemiology, 1998
- PENILE TRAUMA: AN ETIOLOGIC FACTOR IN PEYRONIE'S DISEASE AND ERECTILE DYSFUNCTIONJournal of Urology, 1997
- Fibrin Deposition in Peyronie's Disease PlaqueJournal of Urology, 1997
- The Incidence of Peyronie’s Disease in Rochester, Minnesota, 1950 through 1984Journal of Urology, 1991
- The Natural History of Peyronie’s DiseaseJournal of Urology, 1990
- Factors Associated in the Aetiology of Peyronie's DiseaseBritish Journal of Urology, 1982
- Peyronie's disease: A newly recognized autosomal‐dominant traitAmerican Journal of Medical Genetics, 1982
- Mechanisms of Calcification in Peyronie’s DiseaseJournal of Urology, 1982