Phenolic Compounds and Antimicrobial Activity of Olive (Olea europaea L. Cv. Cobrançosa) Leaves
Top Cited Papers
Open Access
- 26 May 2007
- Vol. 12 (5), 1153-1162
- https://doi.org/10.3390/12051153
Abstract
We report the determination of phenolic compounds in olive leaves by reversed-phase HPLC/DAD, and the evaluation of their in vitro activity against several microorganisms that may be causal agents of human intestinal and respiratory tract infections, namely Gram positive (Bacillus cereus, B. subtilis and Staphylococcus aureus), Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae) and fungi (Candida albicans and Cryptococcus neoformans). Seven phenolic compounds were identified and quantified: caffeic acid, verbascoside, oleuropein, luteolin 7-O-glucoside, rutin, apigenin 7-O-glucoside and luteolin 4’-O-glucoside. At low concentrations olive leafs extracts showed an unusual combined antibacterial and antifungal action, which suggest their great potential as nutraceuticals, particulalry as a source of phenolic compounds.Keywords
This publication has 26 references indexed in Scilit:
- Safety assessment of aqueous olive pulp extract as an antioxidant or antimicrobial agent in foodsFood and Chemical Toxicology, 2006
- Isolation and evaluation of antioxidants from leaves of a Tunisian cultivar olive treeEuropean Journal of Lipid Science and Technology, 2005
- Analysis and quantification of flavonoidic compounds from Portuguese olive (Olea Europaea L.) leaf cultivarsNatural Product Research, 2005
- Countercurrent Supercritical Fluid Extraction and Fractionation of High-Added-Value Compounds from a Hexane Extract of Olive LeavesJournal of Agricultural and Food Chemistry, 2004
- Supplementation of oils with oleanolic acid from the olive leaf (olea europaea)European Journal of Lipid Science and Technology, 2004
- Antioxidant activity of phenolics extracted from Olea europaea L. leavesFood Chemistry, 2000
- On the In-vitro Antimicrobial Activity of Oleuropein and HydroxytyrosolJournal of Pharmacy and Pharmacology, 1999
- Isolation of an angiotensin converting enzyme (ACE) inhibitor from Olea europaea and Olea lanceaPhytomedicine, 1996
- Hypoglycemic Activity of Olive LeafPlanta Medica, 1992
- Vasodilator Effect of Olive LeafPlanta Medica, 1991