Size-sensitive sorting of microparticles through control of flow geometry
- 18 July 2011
- journal article
- research article
- Published by AIP Publishing in Applied Physics Letters
- Vol. 99 (3), 034101
- https://doi.org/10.1063/1.3610940
Abstract
We demonstrate a general concept of flow manipulation in microfluidic environments, based on controlling the shape and position of flow domains in order to force switching and sorting of microparticles without moving parts or changes in design geometry. Using microbubble acoustic streaming, we show that regulation of the relative strength of streaming and a superimposed Poiseuille flow allows for size-selective trapping and releasing of particles, with particle size sensitivity much greater than what is imposed by the length scales of microfabrication. A simple criterion allows for quantitative tuning of microfluidic devices for switching and sorting of particles of desired size.Keywords
This publication has 28 references indexed in Scilit:
- Integrated acoustic and magnetic separation in microfluidic channelsApplied Physics Letters, 2009
- Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devicesLab on a Chip, 2009
- Continuous inertial focusing, ordering, and separation of particles in microchannelsProceedings of the National Academy of Sciences of the United States of America, 2007
- Microfluidics with ultrasound-driven bubblesJournal of Fluid Mechanics, 2006
- A new focusing model and switching approach for electrokinetic flow inside microchannelsJournal of Micromechanics and Microengineering, 2005
- Induced-Charge Electrokinetic Phenomena: Theory and Microfluidic ApplicationsPhysical Review Letters, 2004
- Microfluidic devices for cellomics: a reviewSensors and Actuators B: Chemical, 2003
- Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane)Analytical Chemistry, 1998
- Acoustic streamingJournal of Sound and Vibration, 1978
- Oscillating viscous flowsMathematika, 1965