A practical view of ‘druggability’
Top Cited Papers
- 31 August 2006
- journal article
- review article
- Published by Elsevier BV in Current Opinion in Chemical Biology
- Vol. 10 (4), 357-361
- https://doi.org/10.1016/j.cbpa.2006.06.014
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- Druggability: selecting optimized drug candidatesDrug Discovery Today, 2005
- Assessment of chemical libraries for their druggabilityComputational Biology and Chemistry, 2005
- Lead- and drug-like compounds: the rule-of-five revolutionDrug Discovery Today: Technologies, 2004
- Can the pharmaceutical industry reduce attrition rates?Nature Reviews Drug Discovery, 2004
- A Comparison of Physiochemical Property Profiles of Development and Marketed Oral DrugsJournal of Medicinal Chemistry, 2003
- Selection criteria for drug‐like compoundsMedicinal Research Reviews, 2003
- A structure–Permeability study of small drug-like moleculesBioorganic & Medicinal Chemistry Letters, 2003
- The druggable genomeNature Reviews Drug Discovery, 2002
- Molecular Properties That Influence the Oral Bioavailability of Drug CandidatesJournal of Medicinal Chemistry, 2002
- Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settingsAdvanced Drug Delivery Reviews, 2001