Discovery of novel, non-acidic 1,5-biaryl pyrrole EP1 receptor antagonists
- 1 March 2007
- journal article
- research article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry Letters
- Vol. 17 (5), 1200-1205
- https://doi.org/10.1016/j.bmcl.2006.12.021
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Structure–activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonistsBioorganic & Medicinal Chemistry Letters, 2006
- Discovery of novel biaryl heterocyclic EP1 receptor antagonistsBioorganic & Medicinal Chemistry Letters, 2006
- 2,3-Diarylthiophenes as selective EP1 receptor antagonistsBioorganic & Medicinal Chemistry Letters, 2005
- Latest discoveries in prostaglandin receptor modulatorsExpert Opinion on Therapeutic Patents, 2002
- Chemopreventive effects of ONO-8711, a selective prostaglandin E receptor EP(1) antagonist, on breast cancer development.Carcinogenesis: Integrative Cancer Research, 2001
- Prostanoid Receptors: Subtypes and SignalingAnnual Review of Pharmacology and Toxicology, 2001
- Inhibitory effect of a prostaglandin E receptor subtype EP1 selective antagonist, ONO-8713, on development of azoxymethane-induced aberrant crypt foci in miceCancer Letters, 2000
- Novel two types of orally active EP1 receptor antagonistsProstaglandins & Other Lipid Mediators, 1999
- Prostanoid Receptors: Structures, Properties, and FunctionsPhysiological Reviews, 1999
- 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid,2-[3-[2-(furanylmethyl)thio]-1-oxopropyl]hydrazide (SC-51322): A potent PGE2 antagonist and analgesicBioorganic & Medicinal Chemistry Letters, 1994