Structure–activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonists
- 15 July 2006
- journal article
- research article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry Letters
- Vol. 16 (14), 3657-3662
- https://doi.org/10.1016/j.bmcl.2006.04.073
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1Published by Elsevier BV ,2004
- Membrane-associated prostaglandin E synthase-1 is required for neuropathic painNeuroReport, 2004
- Spinal EP receptors mediating prostaglandin E2-induced mechanical hyperalgesia, thermal hyperalgesia, and touch-evoked allodynia in rats.The Journal of Pain, 2003
- Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthaseProceedings of the National Academy of Sciences of the United States of America, 2003
- Microsomal Prostaglandin E Synthase-1 Is a Major Terminal Synthase That Is Selectively Up-Regulated During Cyclooxygenase-2-Dependent Prostaglandin E2 Production in the Rat Adjuvant-Induced Arthritis ModelPublished by The American Association of Immunologists ,2003
- Prostaglandin E synthaseProstaglandins & Other Lipid Mediators, 2002
- Characterization of EP receptor subtypes responsible for prostaglandin E2‐induced pain responses by use of EP1 and EP3 receptor knockout miceBritish Journal of Pharmacology, 2001
- Prostanoid Receptors: Subtypes and SignalingAnnual Review of Pharmacology and Toxicology, 2001
- The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressureJCI Insight, 2001
- Prostanoid Receptors: Structures, Properties, and FunctionsPhysiological Reviews, 1999