Proteolytic Cleavage of Opa1 Stimulates Mitochondrial Inner Membrane Fusion and Couples Fusion to Oxidative Phosphorylation
Open Access
- 1 April 2014
- journal article
- research article
- Published by Elsevier BV in Cell Metabolism
- Vol. 19 (4), 630-641
- https://doi.org/10.1016/j.cmet.2014.03.011
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in miceThe EMBO Journal, 2012
- The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic ComplexesMolecular Cell, 2011
- Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1The Journal of cell biology, 2009
- Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cellsThe Journal of cell biology, 2009
- Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondriaProceedings of the National Academy of Sciences of the United States of America, 2008
- The mitochondrial respiratory chain is a modulator of apoptosisThe Journal of cell biology, 2007
- Reversible phosphorylation of Drp1 by cyclic AMP‐dependent protein kinase and calcineurin regulates mitochondrial fission and cell deathEMBO Reports, 2007
- Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavageThe Journal of cell biology, 2007
- OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1LThe Journal of cell biology, 2007
- Regulation of mitochondrial morphology through proteolytic cleavage of OPA1The EMBO Journal, 2006