Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1
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Open Access
- 28 December 2009
- journal article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 187 (7), 1023-1036
- https://doi.org/10.1083/jcb.200906084
Abstract
M-AAA proteases cleave OPA1 to ensure a balance of long and short OPA1 isoforms, whereas cleavage by OMA1 causes an accumulation of the short OPA1 variants. (See also companion paper from Head et al. in this issue.)Keywords
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