Evidence supporting paracrine hypothesis for Akt‐modified mesenchymal stem cell‐mediated cardiac protection and functional improvement
Top Cited Papers
Open Access
- 2 February 2006
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 20 (6), 661-669
- https://doi.org/10.1096/fj.05-5211com
Abstract
We previously reported that intramyocardial injection of bone marrow-derived mesenchymal stem cells overexpressing Akt (Akt-MSCs) inhibits ventricular remodeling and restores cardiac function measure...Keywords
This publication has 29 references indexed in Scilit:
- Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarctionBlood, 2004
- Thymosin β4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repairNature, 2004
- Mesenchymal Stem Cells and Their Potential as Cardiac TherapeuticsCirculation Research, 2004
- Molecular and Cell-Based Therapies for Protection, Rescue, and Repair of Ischemic MyocardiumCirculation, 2004
- Plasticity of marrow-derived stem cellsBlood, 2003
- Mesenchymal Progenitor Cells Differentiate into an Endothelial Phenotype, Enhance Vascular Density, and Improve Heart Function in a Rat Cellular Cardiomyoplasty ModelCirculation, 2003
- Adult Cardiac Stem Cells Are Multipotent and Support Myocardial RegenerationCell, 2003
- Myocyte renewal and ventricular remodellingNature, 2002
- The Tetrahymena chaperonin subunit CCTη gene is coexpressed with CCTγ gene during cilia biogenesis and cell sexual reproductionFEBS Letters, 1996
- Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental cardiac failure.JCI Insight, 1995