Overview, prevention and management of chemotherapy extravasation
Open Access
- 1 January 2016
- journal article
- review article
- Published by Baishideng Publishing Group Inc. in World Journal of Clinical Oncology
- Vol. 7 (1), 87-97
- https://doi.org/10.5306/wjco.v7.i1.87
Abstract
Chemotherapy extravasation remains an accidental complication of chemotherapy administration and may result in serious damage to patients. We review in this article the clinical aspects of chemotherapy extravasation and latest advances in definitions, classification, prevention, management and guidelines. We review the grading of extravasation and tissue damage according to various chemotherapeutic drugs and present an update on treatment and new antidotes including dexrazoxane for anthracyclines extravasation. We highlight the importance of education and training of the oncology team for prevention and prompt pharmacological and non-pharmacological management and stress the availability of new antidotes like dexrazoxane wherever anthracyclines are being infused.This publication has 52 references indexed in Scilit:
- Vesicant extravasationNursing2021, 2013
- Extravasation Injuries in AdultsISRN Dermatology, 2013
- American Society of Clinical Oncology/Oncology Nursing Society Chemotherapy Administration Safety StandardsOncology Nursing Forum, 2009
- Infiltration and ExtravasationJournal of Infusion Nursing, 2009
- Infiltration and ExtravasationThe American Journal of Nursing, 2007
- Extravasation InjuriesJournal of Wound, Ostomy & Continence Nursing, 2007
- Extravasations of OxaliplatinJournal of Clinical Oncology, 2003
- Extravasation of paclitaxel into breast tissue from central catheter portSupportive Care in Cancer, 2002
- Hyperbaric Oxygen Therapy in Adriamycin Extravasation: An Experimental Animal StudyAnnals of Plastic Surgery, 2000
- Clinical course and management of accidental adriamycin extravasationCancer, 1977