A unified algorithm for predicting partition coefficients for PBPK modeling of drugs and environmental chemicals
- 15 December 2010
- journal article
- Published by Elsevier BV in Toxicology and Applied Pharmacology
- Vol. 249 (3), 197-207
- https://doi.org/10.1016/j.taap.2010.09.010
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Commentary on ‘‘Toxicity Testing in the 21st Century: A vision and a Strategy’’Human & Experimental Toxicology, 2010
- Evaluation of Selective Competitive Binding of Basic Drugs to .ALPHA.1-Acid Glycoprotein VariantsBiological & Pharmaceutical Bulletin, 2010
- Development of a novel method for predicting human volume of distribution at steady-state of basic drugs and comparative assessment with existing methodsJournal of Pharmaceutical Sciences, 2009
- Toxicity Testing in the 21st Century: Bringing the Vision to LifeToxicological Sciences, 2008
- The cellular structure and lipid/protein composition of adipose tissue surrounding chronically stimulated lymph nodes in ratsJournal of Anatomy, 2003
- COMPARISON OF MODELS FOR THE ESTIMATION OF BIOLOGICAL PARTITION COEFFICIENTSJournal of Toxicology and Environmental Health, Part A, 2002
- HUMAN ALPHA-1-GLYCOPROTEIN AND ITS INTERACTIONS WITH DRUGS†,‡Drug Metabolism Reviews, 2001
- A Tissue Composition-Based Algorithm for Predicting Tissue:Air Partition Coefficients of Organic ChemicalsToxicology and Applied Pharmacology, 1996
- An algorithm for predicting tissue : Blood partition coefficients of organic chemicals fromn‐octanol: Water partition coefficient dataJournal of Toxicology and Environmental Health, 1995
- A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolationArchives of Toxicology, 1993