Commentary on ‘‘Toxicity Testing in the 21st Century: A vision and a Strategy’’
- 8 January 2010
- journal article
- review article
- Published by SAGE Publications in Human & Experimental Toxicology
- Vol. 29 (1), 31-32
- https://doi.org/10.1177/0960327109354662
Abstract
The report of the National Academy of Sciences entitled ‘Toxicity Testing in the 21st Century: A Vision and a Strategy,’ hereinafter referred to as ‘The Report,’ is more of a vision than of a strategy. The present article addresses three observations made on The Report; namely, dose response, PBPK modeling, and in vitro testing. An additional observation this author has of the document is that a role for a scientist who can analyze the big picture is missing from the document. Science today is necessarily composed of specialists in many areas because science today encompasses many diverse, specific fields. Each specialist is in a world of his or her own and unable to integrate all the facts. Must we wait for another Newton or Einstein?Keywords
This publication has 3 references indexed in Scilit:
- Hormesis: Why it is important to toxicology and toxicologistsEnvironmental Toxicology and Chemistry, 2008
- Thermodynamic basis for expressing dose logarithmicallyToxicology and Applied Pharmacology, 2008
- Localization of Drugs in Tissues with Respect to their Physiological ActionsAnnual Review of Pharmacology, 1973