Treatment of Chronic Hepatitis C with Recombinant Interferon Alfa
- 30 November 1989
- journal article
- clinical trial
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 321 (22), 1501-1506
- https://doi.org/10.1056/nejm198911303212203
Abstract
Chronic hepatitis C (non-A, non-B hepatitis) is a common and often progressive viral liver disease. To assess the efficacy of therapy with the antiviral agent interferon alfa, we randomly assigned 166 patients with chronic hepatitis C to treatment with either 3 million or 1 million units of recombinant interferon alfa three times weekly for 24 weeks, or to no treatment.Keywords
This publication has 11 references indexed in Scilit:
- Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis GenomeScience, 1989
- An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B HepatitisScience, 1989
- Acute Unidentified Hepatitis in a Hypogammaglobulinaemic Patient on Intravenous Gammaglobulin Successfully Treated with InterferonActa Medica Scandinavica, 1987
- ALPHA-INTERFERON THERAPY FOR NON-A, NON-B HEPATITIS TRANSMITTED BY GAMMAGLOBULIN REPLACEMENT THERAPYThe Lancet, 1987
- Treatment of Chronic Non-A, Non-B Hepatitis with Recombinant Human Alpha InterferonThe New England Journal of Medicine, 1986
- A Practical Cytopathic Effect/Dye-Uptake Interferon Assay for Routine Use in the Clinical LaboratoryAmerican Journal of Clinical Pathology, 1985
- Non-A, Non-B Posttransfusion Hepatitis—A Decade LaterGastroenterology, 1985
- Treatment of chronic non‐A, non‐B hepatitis with acyclovir: Pilot studyJournal of Medical Virology, 1985
- Sporadic Non-A, Non-B Hepatitis: Frequency and Epidemiology in an Urban U.S. PopulationThe Journal of Infectious Diseases, 1982
- Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitisHepatology, 1981