Recent developments in the field of oxa-Michael reactions
Top Cited Papers
- 28 July 2011
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Chemical Society Reviews
- Vol. 41 (3), 988-999
- https://doi.org/10.1039/c1cs15167c
Abstract
Oxa-Michael reactions, i.e. addition reactions of oxygen nucleophiles to conjugated systems, have traditionally received much less attention from the scientific community compared to the addition of carbon nucleophiles to conjugate acceptor systems (Michael reaction). This was mainly due to lack of reactivity and selectivity of these reactions. Within the last few years however, there has been a remarkable increase in publications focussing on method development as well as applications to natural product synthesis. This tutorial review discusses instructive examples that have substantially broadened the scope of oxa-Michael reactions.Keywords
This publication has 64 references indexed in Scilit:
- Discovery of the Michael ReactionEuropean Journal of Organic Chemistry, 2010
- Organocatalytic Asymmetric Aza‐Michael AdditionsChemistry – A European Journal, 2009
- Asymmetric Enamine CatalysisChemical Reviews, 2007
- Recent Advances in Metal-Catalyzed Asymmetric Conjugate AdditionsSynthesis, 2007
- Asymmetric Sulfa-Michael AdditionsSynthesis, 2007
- Modern Aldol Methods for the Total Synthesis of PolyketidesAngewandte Chemie-International Edition, 2006
- Strategies and approaches for constructing 1-oxadecalinsTetrahedron, 2006
- The Phospha‐Michael Addition in Organic SynthesisEuropean Journal of Organic Chemistry, 2005
- THE ASYMMETRICAZA-MICHAEL REACTION. A REVIEWOrganic Preparations and Procedures International, 2005
- Ueber die künstliche Aepfelsäure aus FumarsäureEuropean Journal of Organic Chemistry, 1878