The antioxidant action of tamoxifen and its metabolites Inhibition of lipid peroxidation
- 24 April 1990
- journal article
- Published by Wiley in FEBS Letters
- Vol. 263 (2), 192-194
- https://doi.org/10.1016/0014-5793(90)81371-t
Abstract
The anti-oestrogen drug tamoxifen is an inhibitor of lipid peroxidation in rat liver microsomes and in phospholipid liposomes. Its cis isomer and N-desmethyl form are weaker inhibitors, but 4-hydroxytamoxifen is much more powerful. It is possible that the antioxidant property of tamoxifen might contribute to its biological actions.This publication has 21 references indexed in Scilit:
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