Estrogens as natural antioxidants of membrane phospholipid peroxidation
- 1 January 1987
- journal article
- Published by Wiley in FEBS Letters
- Vol. 210 (1), 37-39
- https://doi.org/10.1016/0014-5793(87)81293-0
Abstract
Estrogens, such as estrone, estradiol and estriol, were tested as possible antioxidants of lipid peroxidation induced by Fe3+-ADP-adriamycin or Fe3+-ADP-ascorbate. The estrogens with phenolic structure possessed substantial activities with respect to the inhibition of lipid peroxidation. Concentrations of estradiol and estriol required to achieve 50% inhibition of membrane phospholipid peroxidation were about 4- and 6-times that of α-tocopherol, respectivelyKeywords
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