Chemical and structural lessons from recent successes in protein–protein interaction inhibition (2P2I)
- 31 August 2011
- journal article
- review article
- Published by Elsevier BV in Current Opinion in Chemical Biology
- Vol. 15 (4), 475-481
- https://doi.org/10.1016/j.cbpa.2011.05.024
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- Large-scale protein interactome mapping: strategies and opportunitiesExpert Review of Proteomics, 2010
- Design and synthesis of a simplified inhibitor for XIAP-BIR3 domainBioorganic & Medicinal Chemistry Letters, 2009
- Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2Biochemical and Biophysical Research Communications, 2009
- An empirical framework for binary interactome mappingNature Methods, 2008
- BCL-2 family antagonists for cancer therapyNature Reviews Drug Discovery, 2008
- Non‐peptidic small molecule inhibitors against Bcl‐2 for cancer therapyJournal of Cellular Physiology, 2008
- Drug-like inhibitors of protein-protein interactions: a structural examination of effective protein mimicry.Current Protein & Peptide Science, 2008
- Estimating the size of the human interactomeProceedings of the National Academy of Sciences of the United States of America, 2008
- Reaching for high-hanging fruit in drug discovery at protein–protein interfacesNature, 2007
- How many drug targets are there?Nature Reviews Drug Discovery, 2006