Two Neolignan Glucosides and Antihistamine Release Activities from Bidens parviflora WILLD.
- 1 January 2006
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 54 (8), 1190-1192
- https://doi.org/10.1248/cpb.54.1190
Abstract
Two new neolignan glucosides, bidenlignasides A (1) and B (2), were isolated from the whole plant of Bidens parviflora WILLD. The structures of the two new compounds 1 and 2 established to be 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-[5E-(3-hydroxypropenyl)-3-methoxy-2-O-beta-D-glucosyl)phenyl] propan-1-one and 3-{3-[1,3-dihydroxy-3-(4-hydroxy-3-methoxyphenyl)propyl]-4-hydroxy-5-methoxyphenyl}-allyl-O-beta-D-glucuside, respectively, on the basis of spectral and chemical evidence. Compounds 1 and 2 were found to inhibit histamine release from peritoneal exudate mast cells induced by antigen-antibody reaction.Keywords
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