Transarterial Chemoembolization Complicated by Deteriorating Hepatic Function
- 16 June 2011
- journal article
- Published by Georg Thieme Verlag KG in Seminars in Interventional Radiology
- Vol. 28 (02), 198-201
- https://doi.org/10.1055/s-0031-1280664
Abstract
Worsening hepatic function is a well-known potential complication of chemoembolization and occurs in up to 58% of patients undergoing chemoembolization. Although liver function returns to baseline levels within 3–4 weeks in the majority of patients, fulminant liver failure and death occur with a reported frequency of ~2–10%. Poor performance status, portal vein obstruction, biliary obstruction, extensive tumor burden, and Child-Pugh status B or C are among factors predisposing to an increased risk of transient or fulminant hepatic failure, with Child-Pugh status being the most accurate. Unless the patient is a candidate for liver transplantation, treatment for hepatic failure is limited to supportive measures.Keywords
This publication has 12 references indexed in Scilit:
- Role of intra‐arterial hepatic chemotherapy in the treatment of colorectal cancer metastasesJournal of Surgical Oncology, 2010
- Salvage Therapy for Liver-dominant Colorectal Metastatic Adenocarcinoma: Comparison between Transcatheter Arterial Chemoembolization versus Yttrium-90 RadioembolizationJournal of Vascular and Interventional Radiology, 2009
- Chemoembolization of hepatic malignancyAbdominal Radiology, 2008
- Transcatheter Arterial Chemoembolization: Current Technique and Future PromiseTechniques in Vascular and Interventional Radiology, 2007
- Transarterial Therapy for Hepatocellular Carcinoma: Which Technique Is More Effective? A Systematic Review of Cohort and Randomized StudiesCardioVascular and Interventional Radiology, 2006
- Prognostic Accuracy of 12 Liver Staging Systems in Patients with Unresectable Hepatocellular Carcinoma Treated with Transarterial ChemoembolizationJournal of Vascular and Interventional Radiology, 2006
- Chemoembolization for hepatic metastasesTechniques in Vascular and Interventional Radiology, 2002
- Risk of hepatic failure after transcatheter arterial chemoembolization for hepatocellular carcinoma: predictive value of the monoethylglycinexylidide testThe American Journal of Gastroenterology, 2002
- Cytolysis following chemoembolization for hepatocellular carcinomaBritish Journal of Surgery, 1999
- Hepatic tumors: predisposing factors for complications of transcatheter oily chemoembolization.Radiology, 1996