Toward new criteria for systemic lupus erythematosus—a standpoint
Open Access
- 31 May 2016
- journal article
- review article
- Published by SAGE Publications in Lupus
- Vol. 25 (8), 805-811
- https://doi.org/10.1177/0961203316644338
Abstract
While clearly different in their aims and means, classification and diagnosis both try to accurately label the disease patients are suffering from. For systemic lupus erythematosus (SLE), this is complicated by the multi-organ nature of the disease and by our incomplete understanding of its pathophysiology. Hallmarks of SLE are the presence of antinuclear antibodies (ANA), and multiple immune-mediated organ symptoms that are largely independent. In an attempt to overcome limitations of the current sets of SLE classification criteria, a new four-phase approach is being developed, which is jointly supported by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR). This review attempts to delineate the performance of the current sets of criteria, the reasons for the decision for classification, and not diagnostic, criteria, and to provide a background of the current approach taken.This publication has 38 references indexed in Scilit:
- SAT0415 Performance of Anti-Nuclear Antibodies (ANA) for Classifying Systemic Lupus Erythematosus (SLE): A Systematic Literature Review and Meta-Regression of Diagnostic DataAnnals Of The Rheumatic Diseases, 2015
- Lots of autoantibodies equal lupus?Arthritis Research & Therapy, 2013
- Autoantibody profiling to follow evolution of lupus syndromesArthritis Research & Therapy, 2012
- Systemic Lupus ErythematosusThe New England Journal of Medicine, 2011
- Systemic Lupus ErythematosusThe New England Journal of Medicine, 2008
- Deposition of nucleosomal antigens (histones and DNA) in the epidermal basement membrane in human lupus nephritisArthritis & Rheumatism, 2003
- Morbidity and Mortality in Systemic Lupus Erythematosus During a 5-Year Period: A Multicenter Prospective Study of 1,000 PatientsMedicine, 1999
- Updating the American college of rheumatology revised criteria for the classification of systemic lupus erythematosusArthritis & Rheumatism, 1997
- The 1982 revised criteria for the classification of systemic lupus erythematosusArthritis & Rheumatism, 1982
- Immunologic Factors and Clinical Activity in Systemic Lupus ErythematosusThe New England Journal of Medicine, 1968