Systemic Lupus Erythematosus
Top Cited Papers
- 28 February 2008
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 358 (9), 929-939
- https://doi.org/10.1056/nejmra071297
Abstract
Systemic lupus erythematosus has many guises, but the unifying feature is the presence of antibodies against double-stranded DNA in almost all patients. This review provides data that show that such autoantibodies cause the renal lesions of systemic lupus erythematosus, and it emphasizes the importance of histones, histone fragments, and other nuclear autoantigens.Keywords
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