FT-IR spectroscopic analysis of normal and cancerous tissues of esophagus
Open Access
- 1 January 2003
- journal article
- Published by Baishideng Publishing Group Inc. in World Journal of Gastroenterology
- Vol. 9 (9), 1897-9
- https://doi.org/10.3748/wjg.v9.i9.1897
Abstract
AIM: To investigate the special Fourier transform infrared spectroscopy (FT-IR) spectra in normal and cancerous tissues of esophagus. METHODS: Twenty-seven pairs of normal and cancerous tissues of esophagus were studied by using FT-IR and the special spectra characteristics were analyzed in different tissues. RESULTS: Different spectra were found in normal and cancerous tissues. The peak at 1550/cm was weak and wide in cancerous tissues but strong and high in normal tissues.The ratio of I 1647/I 1550 was 2.0 in normal tissues and 2.36 in cancerous tissues (P < 0.05). The ratio of I 1550/I 1080 was 4.5 in normal tissues and 3.4 in cancerous tissues (P < 0.01). The peak at 1453/cm was higher than at 1402/cm in normal tissue and lower than at 1402/cm in cancerous tissues. CONCLUSION: The results indicate that FTIR may be used in clinical diagnosis.Keywords
This publication has 32 references indexed in Scilit:
- Overexpression of Glut‐1 and increased glucose metabolism in tumors are associated with a poor prognosis in patients with oral squamous cell carcinomaCancer, 2003
- R‐Ras promotes tumor growth of cervical epithelial cellsCancer, 2003
- Removal of blood components from cervical smears: Implications for cancer diagnosis using FTIR spectroscopyPeptide Science, 2002
- Enhanced CpG Mutability and Tumorigenesis in MBD4-Deficient MiceScience, 2002
- Infrared Spectral Features of Exfoliated Cervical Cells, Cervical Adenocarcinoma Tissue, and an Adenocarcinoma Cell Line (SiSo)Gynecologic Oncology, 2002
- Surface enhanced IR absorption of nucleic acids from tumor cells: FTIR reflectance studyPeptide Science, 2002
- Diagnostic potential of Fourier-transform infrared microspectroscopy and advanced computational methods in colon cancer patientsJournal of Biomedical Optics, 2002
- Detailed account of confounding factors in interpretation of FTIR spectra of exfoliated cervical cellsPeptide Science, 2002
- Fourier transform infrared (FT-IR) mid-IR spectroscopy separates normal and malignant tissue from the colon and stomachGastroenterology, 2000
- Diagnosis and surgery of esophageal cancerCritical Reviews in Oncology/Hematology, 1998