Use of Murine Norovirus as a Surrogate To Evaluate Resistance of Human Norovirus to Disinfectants
- 15 May 2008
- journal article
- Published by American Society for Microbiology in Applied and Environmental Microbiology
- Vol. 74 (10), 3315-3318
- https://doi.org/10.1128/aem.02148-07
Abstract
Murine norovirus (MNV) was used as a surrogate to study resistance of human norovirus to disinfectants used in hospitals. MNV was sensitive to alcohol, alcohol hand rubs, bleach, and povidone iodine-based disinfectant. Real-time reverse transcription-PCR results indicated that the presence of viral RNA did not correlate with the presence of infectious virus.Keywords
This publication has 28 references indexed in Scilit:
- Detection of Murine Norovirus 1 by Using Plaque Assay, Transfection Assay, and Real-Time Reverse Transcription-PCR before and after Heat ExposureApplied and Environmental Microbiology, 2008
- Chlorine Sensitivity of Feline Calicivirus, a Norovirus SurrogateApplied and Environmental Microbiology, 2007
- Evaluation of Liquid- and Fog-Based Application of Sterilox Hypochlorous Acid Solution for Surface Inactivation of Human NorovirusApplied and Environmental Microbiology, 2007
- Cleavage Map and Proteolytic Processing of the Murine Norovirus Nonstructural Polyprotein in Infected CellsJournal of Virology, 2006
- Comparative efficacy of ethanol and isopropanol against feline calicivirus, a norovirus surrogateAmerican Journal of Infection Control, 2006
- Efficacy of three ethanol-based hand rubs against feline calicivirus, a surrogate virus for norovirusJournal of Hospital Infection, 2005
- Inactivation of Enteric Adenovirus and Feline Calicivirus by Chlorine DioxideApplied and Environmental Microbiology, 2005
- Replication of Norovirus in Cell Culture Reveals a Tropism for Dendritic Cells and MacrophagesPLoS Biology, 2004
- Capsid Functions of Inactivated Human Picornaviruses and Feline CalicivirusApplied and Environmental Microbiology, 2003
- RT-PCR identification and typing of astroviruses and Norwalk-like viruses in hospitalized patients with gastroenteritis: evidence of nosocomial infectionsJournal of Clinical Virology, 2000