Sordera neurosensorial por mutación del gen MYH14. Descripción de un caso

Abstract

Introduction and objective: Hereditary causes are responsible for half of cases of sensorineural hearing loss in young people Mutation of the MYH14 gene is autosomal dominant. Description: A 33 years-old male patient with moderate to severe bilateral sensorineural hearing loss. Genetic study revealed MYH14 gene mutation. Discussion: This is a case of post-lingual sensorineural deafness, compatible with autosomal dominant inheritance. MYH14 mutation seems to increase susceptibility to acoustic trauma, which may justify the late onset of hearing loss. Conclusions: MYH14 mutation is, probably, a cause for hearing loss. Genetic study has, therefore, a growing importance.