Plant Polyphenols as Dietary Antioxidants in Human Health and Disease
Top Cited Papers
Open Access
- 1 January 2009
- journal article
- review article
- Published by Hindawi Limited in Oxidative Medicine and Cellular Longevity
- Vol. 2 (5), 270-278
- https://doi.org/10.4161/oxim.2.5.9498
Abstract
Polyphenols are secondary metabolites of plants and are generally involved in defense against ultraviolet radiation or aggression by pathogens. In the last decade, there has been much interest in the potential health benefits of dietary plant polyphenols as antioxidant. Epidemiological studies and associated meta-analyses strongly suggest that long term consumption of diets rich in plant polyphenols offer protection against development of cancers, cardiovascular diseases, diabetes, osteoporosis and neurodegenerative diseases. Here we present knowledge about the biological effects of plant polyphenols in the context of relevance to human health.Keywords
Funding Information
- Council of Scientific and Industrial Research
This publication has 82 references indexed in Scilit:
- Multitargeted therapy of cancer by green tea polyphenolsCancer Letters, 2008
- A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in MicePLOS ONE, 2008
- Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetesNature, 2007
- Resveratrol: A review of preclinical studies for human cancer preventionToxicology and Applied Pharmacology, 2007
- Mediterranean diet and Alzheimer disease mortalityNeurology, 2007
- Fruit and Vegetable Juices and Alzheimer’s Disease: The Kame ProjectThe American Journal of Medicine, 2006
- Fast Access of Some Grape Pigments to the BrainJournal of Agricultural and Food Chemistry, 2005
- Dietary Intake of Soy Genistein is Associated with Lung Function in Patients with AsthmaJournal of Asthma, 2004
- The gastrointestinal tract: A major site of antioxidant action?Free Radical Research, 2000
- Bioavailability of flavonoids from teaCritical Reviews in Food Science and Nutrition, 1997