Structure of two human ovarian inhibins

Abstract

The complete amino acid sequences of two forms of human ovarian inhibin have been determined through cloning and nucleotide sequencing of cDNAs encoding their individual subunit precursors. The α subunit common to both forms of human inhibin is homologous (84 percent conserved) to its equivalent porcine α subunit; the subunits which are different in both inhibins (β_A and β_B) are identical to their porcine equivalents in all but one of 232 sequence positions.