Molecular Characterization of Ofloxacin-Resistant Mycobacterium tuberculosis Strains from Russia
- 1 August 2008
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 52 (8), 2937-2939
- https://doi.org/10.1128/aac.00036-08
Abstract
In this work, we studied the variation in the gyrA and gyrB genes in ofloxacin- and multidrug-resistant Mycobacterium tuberculosis strains circulating in northwest Russia. Comparison with spoligotyping data suggested that similar to the spread of multidrug-resistant tuberculosis, the spread of fluoroquinolone-resistant tuberculosis in Russia may be due, at least partly, to the prevalence of the Beijing genotype in a local population of M. tuberculosis .Keywords
This publication has 21 references indexed in Scilit:
- Importance of the Efflux Pump Systems in the Resistance of Mycobacterium tuberculosis to Fluoroquinolones and LinezolidChemotherapy, 2007
- Hypervariable loci that enhance the discriminatory ability of newly proposed 15-loci and 24-loci variable-number tandem repeat typing method onMycobacterium tuberculosisstrains predominated by the Beijing familyFEMS Microbiology Letters, 2007
- Genetic and phenotypic characterization of drug-resistant Mycobacterium tuberculosis isolates in Hong KongJournal of Antimicrobial Chemotherapy, 2007
- Emergence of Ofloxacin Resistance in Mycobacterium tuberculosis Clinical Isolates from China as Determined by gyrA Mutation Analysis Using Denaturing High-Pressure Liquid Chromatography and DNA SequencingJournal of Clinical Microbiology, 2006
- Proposal for Standardization of Optimized Mycobacterial Interspersed Repetitive Unit-Variable-Number Tandem Repeat Typing ofMycobacterium tuberculosisJournal of Clinical Microbiology, 2006
- Evaluation of the rpoB macroarray assay to detect rifampin resistance in Mycobacterium tuberculosis in Beijing, ChinaEuropean Journal of Clinical Microbiology & Infectious Diseases, 2006
- Trends in fluoroquinolone resistance of Mycobacterium tuberculosis complex in a Taiwanese medical centre: 1995–2003Journal of Antimicrobial Chemotherapy, 2005
- PCR-Based Methodology for Detecting Multidrug-Resistant Strains of Mycobacterium tuberculosis Beijing Family Circulating in RussiaEuropean Journal of Clinical Microbiology & Infectious Diseases, 2003
- Detection of embB306 Mutations in Ethambutol-Susceptible Clinical Isolates of Mycobacterium tuberculosis from Northwestern Russia: Implications for Genotypic Resistance TestingJournal of Clinical Microbiology, 2002
- Molecular Characterization of Multidrug-Resistant Isolates of Mycobacterium tuberculosis from Patients in North IndiaAntimicrobial Agents and Chemotherapy, 2002