Evaluation of a quantitative RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high throughput system
Top Cited Papers
Open Access
- 5 March 2020
- journal article
- research article
- Published by European Centre for Disease Control and Prevention (ECDC) in Eurosurveillance
- Vol. 25 (9), 2000152-22
- https://doi.org/10.2807/1560-7917.es.2020.25.9.2000152
Abstract
Facing the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), high-volume respiratory testing is demanded in laboratories worldwide. We evaluated the performance of a molecular assay for the detection of SARS-CoV-2 on a high-throughput platform, the cobas 6800, using the ‘open channel’ for integration of a laboratory-developed assay. We observed good analytical performance in clinical specimens. The fully automated workflow enables high-throughput testing with minimal hands-on time, while offering fast and reliable results.Keywords
This publication has 14 references indexed in Scilit:
- Evaluation of the Performance of the Cobas CT/NG Test for Use on the Cobas 6800/8800 Systems for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae in Male and Female Urogenital SamplesJournal of Clinical Microbiology, 2019
- Clinical Validation of the cobas HPV Test on the cobas 6800 System for the Purpose of Cervical ScreeningJournal of Clinical Microbiology, 2019
- The European Virus Archive goes global: A growing resource for researchAntiviral Research, 2018
- Diagnosis and monitoring of HCV infection using the cobas ® HCV test for use on the cobas ® 6800/8800 systemsJournal of Clinical Virology, 2018
- Zika virus RNA polymerase chain reaction on the utility channel of a commercial nucleic acid testing systemTransfusion, 2018
- High-throughput testing of urogenital and extragenital specimens for detection of Chlamydia trachomatis and Neisseria gonorrhoeae with cobas® CT/NGEuropean Journal of Microbiology and Immunology, 2017
- Multicenter Comparison Study of both Analytical and Clinical Performance across Four Roche Hepatitis C Virus RNA Assays Utilizing Different PlatformsJournal of Clinical Microbiology, 2017
- The cobas® 6800/8800 System: a new era of automation in molecular diagnosticsExpert Review of Molecular Diagnostics, 2016
- Ten years of R&D and full automation in molecular diagnosisFuture Microbiology, 2016
- War StoriesScience, 2013