Microfluidic Chips for Immunoassays
- 12 June 2013
- journal article
- review article
- Published by Annual Reviews in Annual Review of Analytical Chemistry
- Vol. 6 (1), 119-141
- https://doi.org/10.1146/annurev-anchem-062012-092616
Abstract
The use of microfluidic chips for immunoassays has been extensively explored in recent years. The combination of immunoassays and microfluidics affords a promising platform for multiple, sensitive, and automatic point-of-care (POC) diagnostics. In this review, we focus on the description of recent achievements in microfluidic chips for immunoassays categorized by their detection method. Following a brief introduction to the basic principles of each detection method, we examine current microfluidic immunosensor detection systems in detail. We also highlight interesting strategies for sensitive immunosensing configurations, multiplexed analysis, and POC diagnostics in microfluidic immunosensors.Keywords
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