Broadband terahertz time-domain spectroscopy of drugs-of-abuse and the use of principal component analysis
- 22 May 2009
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in The Analyst
- Vol. 134 (8), 1658-1668
- https://doi.org/10.1039/b817839a
Abstract
Terahertz frequency time-domain spectroscopy has been used to analyse a wide range of samples containing cocaine hydrochloride, heroin and ecstasy – common drugs-of-abuse. We investigated real-world samples seized by law enforcement agencies, together with pure drugs-of-abuse, and pure drugs-of-abuse systematically adulterated in the laboratory to emulate real-world samples. In order to investigate the feasibility of automatic spectral recognition of such illicit materials by terahertz spectroscopy, principal component analysis was employed to cluster spectra of similar compounds.Keywords
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