Demyeliating neuropathy and monoclonal IgM antibody to myelin‐associated glycoprotein
- 1 January 1983
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurology
- Vol. 33 (1), 19
- https://doi.org/10.1212/wnl.33.1.19
Abstract
We studied a patient with demyelinating neuropathy and monoclonal IgM kappa antibody to the major myelin-associated glycoprotein (MAG). Binding of this monoclonal antibody to the myelin antigen was demonstrated by imimunoelectroblot. Binding to MAG seemed to be specific, because it was completely inhibited by MAG isolated from human myelin. Immunostaining was observed with MAG from CNS and peripheral nervous system myelin.This publication has 3 references indexed in Scilit:
- Polyneuropathy in Waldenström's MacroglobulinemiaArchives of Neurology, 1978
- A rapid procedure for selectively isolating the major glycoprotein from purified rat brain myelinBiochemical Journal, 1977
- PROTEINS AND GLYCOPROTEINS IN MYELIN PURIFIED FROM THE DEVELOPING BOVINE AND HUMAN CENTRAL NERVOUS SYSTEMSJournal of Neurochemistry, 1977