Polyneuropathy in Waldenström's Macroglobulinemia
- 1 July 1978
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 35 (7), 423-425
- https://doi.org/10.1001/archneur.1978.00500310025005
Abstract
• A chronic sensory neuropathy was the initial symptom in a case of Waldenström's macroglobulinemia in a 53-year-old woman. Ultrastructural analysis of a biopsied peripheral nerve revealed a modification of the lamellar structure of the myelin sheath. Immunofluorescent microscopy showed IgM-positive deposits on the myelin sheath. The monoclonal globulin (M component) present in the myelin appears to be a causative factor in the neuropathy.This publication has 4 references indexed in Scilit:
- A Monoclonal IgM Protein with Antibody-like Activity for Human AlbuminJCI Insight, 1974
- Demyelinating neuropathy in macrocryoglobulinemiaNeurology, 1966
- Serum Hyperviscosity SyndromeJAMA, 1965
- Incipient myelomatosis or «essential« hyperglobulinemia with fibrinogenopenia — a new syndrome?Acta Medica Scandinavica, 1944