Evaluation of the innate immune-stimulating activity of amazake using a silkworm muscle contraction assay
- 1 January 2017
- journal article
- Published by International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA) in Drug Discoveries & Therapeutics
- Vol. 11 (5), 288-290
- https://doi.org/10.5582/ddt.2017.01051
Abstract
We evaluated the innate immune-stimulating activity of amazake using a silkworm muscle contraction assay. Sake cake, a raw material used to make amazake, had high innate immunity-stimulating activity, whereas rice malt, another raw material used to make amazake, did not, even after fermentation. These results suggest that the silkworm muscle contraction assay is a useful tool to screen foods with high innate immune-stimulating activity and that amazake made from sake cake has immunomodulatory potential.Keywords
This publication has 12 references indexed in Scilit:
- Consumption of Dairy Yogurt Containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum Improves Immune Function Including Natural Killer Cell ActivityNutrients, 2017
- Using silkworms as a laboratory animal to evaluate medicines and foods.Drug Discoveries & Therapeutics, 2016
- Evaluation of innate immune stimulating activity of polysaccharides using a silkworm (Bombyx mori) muscle contraction assayDrug Discoveries & Therapeutics, 2012
- Purification of innate immunostimulant from green tea using a silkworm muscle contraction assayDrug Discoveries & Therapeutics, 2011
- Activation of the Silkworm Cytokine by Bacterial and Fungal Cell Wall Components via a Reactive Oxygen Species-triggered MechanismPublished by Elsevier BV ,2008
- Identification and Kinetic Study of Tyrosinase Inhibitors Found in Sake LeesJournal of Agricultural and Food Chemistry, 2006
- Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general populationThe Lancet, 2000
- Effects of a Fermented Milk Drink ContainingLactobacillus caseiStrain Shirota on the Immune System in Healthy Human SubjectsBioscience, Biotechnology, and Biochemistry, 2000
- Modulation of a specific humoral immune response and changes in intestinal flora mediated through fermented milk intakeFEMS Immunology & Medical Microbiology, 1994
- Antihypertensive Effects of Peptide in Sake and Its By-products on Spontaneously Hypertensive RatsBioscience, Biotechnology, and Biochemistry, 1994