NADPH oxidase-dependent formation of reactive oxygen species contributes to transforming growth factor β1-induced epithelial-mesenchymal transition in rat peritoneal mesothelial cells, and the role of astragalus intervention
- 22 October 2012
- journal article
- research article
- Published by Springer Science and Business Media LLC in Chinese Journal of Integrated Medicine
- Vol. 20 (9), 667-674
- https://doi.org/10.1007/s11655-012-1176-x
Abstract
To investigate the role of nicotinamide-adenine dinucleotide phosphate (NADPH) oxidasedependent formation of reactive oxygen species (ROS) in the transforming growth factor β1 (TGF-β1)-induced epithelial-mesenchymal transition (EMT) in rat peritoneal mesothelial cells (RPMCs), and the effect of Astragalus injection (AGI) intervention.Keywords
This publication has 24 references indexed in Scilit:
- Signalling pathways from NADPH oxidase-4 to idiopathic pulmonary fibrosisThe International Journal of Biochemistry & Cell Biology, 2011
- Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidasesKidney International, 2011
- Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in miceToxicology and Applied Pharmacology, 2011
- Reactive Oxygen Species Are Required for Maintenance and Differentiation of Primary Lung Fibroblasts in Idiopathic Pulmonary FibrosisPLOS ONE, 2010
- Compound Astragalus and Salvia miltiorrhiza Extract exerts anti-fibrosis by mediating TGF-β/Smad signaling in myofibroblastsJournal of Ethnopharmacology, 2008
- Fibroblast Foci Are Not Discrete Sites of Lung Injury or RepairAmerican Journal of Respiratory and Critical Care Medicine, 2006
- Role of Reactive Oxygen Species in TGF-β1-Induced Mitogen-Activated Protein Kinase Activation and Epithelial-Mesenchymal Transition in Renal Tubular Epithelial CellsJournal of the American Society of Nephrology, 2005
- Peritoneal Dialysis and Epithelial-to-Mesenchymal Transition of Mesothelial CellsThe New England Journal of Medicine, 2003
- A New Superoxide-generating Oxidase in Murine OsteoclastsPublished by Elsevier BV ,2001
- A Novel Superoxide-producing NAD(P)H Oxidase in KidneyPublished by Elsevier BV ,2001