Peritoneal Dialysis and Epithelial-to-Mesenchymal Transition of Mesothelial Cells

Abstract
During continuous ambulatory peritoneal dialysis, the peritoneum is exposed to bioincompatible dialysis fluids that cause denudation of mesothelial cells and, ultimately, tissue fibrosis and failure of ultrafiltration. However, the mechanism of this process has yet to be elucidated.