Safety and efficacy of aneurysm treatment with WEB: results of the WEBCAST study
Top Cited Papers
- 1 May 2016
- journal article
- clinical trial
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 124 (5), 1250-1256
- https://doi.org/10.3171/2015.2.jns142634
Abstract
OBJECT WEB is an innovative intrasaccular treatment for intracranial aneurysms. Preliminary series have shown good safety and efficacy. The WEB Clinical Assessment of Intrasaccular Aneurysm Therapy (WEBCAST) trial is a prospective European trial evaluating the safety and efficacy of WEB in wide-neck bifurcation aneurysms. METHODS Patients with wide-neck bifurcation aneurysms for which WEB treatment was indicated were included in this multicentergood clinical practices study. Clinical data including adverse events and clinical status at 1 and 6 months were collected and independently analyzed by a medical monitor. Six-month follow-up digital subtraction angiography was also performed and independently analyzed by a core laboratory. Success was defined at 6 months as complete occlusion or stable neck remnant, no worsening in angiographic appearance from postprocedure, and no retreatment performed or planned. RESULTS Ten European neurointerventional centers enrolled 51 patients with 51 aneurysms. Treatment w...Keywords
This publication has 18 references indexed in Scilit:
- Endovascular Treatment of Intracranial AneurysmsStroke, 2013
- Cerecyte Coil TrialStroke, 2012
- Intrasaccular Flow-Disruption Treatment of Intracranial Aneurysms: Preliminary Results of a Multicenter Clinical StudyAmerican Journal of Neuroradiology, 2012
- Endovascular Treatment of Ruptured Intracranial Aneurysms: Factors Affecting Midterm Quality Anatomic Results: Analysis in a Prospective, Multicenter Series of Patients (CLARITY)American Journal of Neuroradiology, 2012
- Mid-Term Anatomic Results after Endovascular Treatment of Ruptured Intracranial Aneurysms with Guglielmi Detachable Coils and Matrix Coils: Analysis of the CLARITY SeriesAmerican Journal of Neuroradiology, 2011
- Results of Embolization Used as the First Treatment Choice in a Consecutive Nonselected Population of Ruptured Aneurysms: Clinical Results of the Clarity GDC StudyNeurosurgery, 2011
- Hydrogel-coated coils versus bare platinum coils for the endovascular treatment of intracranial aneurysms (HELPS): a randomised controlled trialThe Lancet, 2011
- Flow diverter stents in the treatment of intracranial aneurysms: Where are we?Journal of Neuroradiology, 2011
- Immediate Clinical Outcome of Patients Harboring Unruptured Intracranial Aneurysms Treated by Endovascular ApproachStroke, 2008
- International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trialThe Lancet, 2002