High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
Top Cited Papers
Open Access
- 1 December 2015
- journal article
- research article
- Published by Elsevier BV in Cell
- Vol. 163 (6), 1515-1526
- https://doi.org/10.1016/j.cell.2015.11.015
Abstract
No abstract availableThis publication has 47 references indexed in Scilit:
- An ecosystem of cancer cell line factories to support a cancer dependency mapNature Reviews Genetics, 2015
- Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and MetastasisCell, 2015
- Organoid Models of Human and Mouse Ductal Pancreatic CancerCell, 2014
- Effects of metformin and other biguanides on oxidative phosphorylation in mitochondriaBiochemical Journal, 2014
- Epigenetic and genetic features of 24 colon cancer cell linesOncogenesis, 2013
- Targeted genome engineering in human cells with the Cas9 RNA-guided endonucleaseNature Biotechnology, 2013
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivityNature, 2012
- RAS Interaction with PI3K: More Than Just Another Effector PathwayGenes & Cancer, 2011
- A human MAP kinase interactomeNature Methods, 2010
- Extension of Life-Span by Introduction of Telomerase into Normal Human CellsScience, 1998