Sequence of pNL194, a 79.3-Kilobase IncN Plasmid Carrying the bla VIM-1 Metallo-β-Lactamase Gene in Klebsiella pneumoniae
- 1 October 2010
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 54 (10), 4497-4502
- https://doi.org/10.1128/aac.00665-10
Abstract
The nucleotide sequence of pNL194, a VIM-1-encoding plasmid, is described in this study. pNL194 (79,307 bp) comprised an IncN-characteristic segment (38,940 bp) and a mosaic structure (40,367 bp) including bla VIM-1 , aacA7 , aadA1 , aadA2 , dfrA1 , dfrA12 , aphA1 , strA , strB , and sul1 . Tn 1000 or Tn 5501 insertion within fipA probably facilitated recruitment of additional mobile elements carrying resistance genes.Keywords
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