IS Ecp1 -Mediated Transposition and Homologous Recombination Can Explain the Context of bla CTX-M-62 Linked to qnrB2
- 1 July 2010
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 54 (7), 3039-3042
- https://doi.org/10.1128/aac.00041-10
Abstract
bla CTX-M-62 , a C508T variant of bla CTX-M-3b , was transferred from Klebsiella pneumoniae JIE137 on a conjugative plasmid together with a class 1 integron containing the dfrA12 - gcuF - aadA2 cassette array, IS CR1 , and qnrB2 . bla CTX-M-62 lies between intact and rearranged copies of IS Ecp1 in a configuration that can be explained by a combination of transposition and homologous recombination and which also illustrates the ability of IS Ecp1 to mobilize an adjacent gene as part of transposition units of different sizes.This publication has 23 references indexed in Scilit:
- Comparative Genomics of the IncA/C Multidrug Resistance Plasmid FamilyJournal of Bacteriology, 2009
- Identification of plasmids by PCR-based replicon typingJournal of Microbiological Methods, 2005
- IS Ecp1B -Mediated Transposition of bla CTX-M in Escherichia coliAntimicrobial Agents and Chemotherapy, 2005
- Chromosome-Encoded CTX-M-3 from Kluyvera ascorbata : a Possible Origin of Plasmid-Borne CTX-M-1-Derived CefotaximasesAntimicrobial Agents and Chemotherapy, 2004
- The first characterization of extended-spectrum -lactamase-producing Salmonella in JapanJournal of Antimicrobial Chemotherapy, 2004
- Insertion Sequence IS Ecp1B Is Involved in Expression and Mobilization of a bla CTX-M β-Lactamase GeneAntimicrobial Agents and Chemotherapy, 2003
- In34, a Complex In5 Family Class 1 Integron Containing orf513 and dfrA10Antimicrobial Agents and Chemotherapy, 2003
- Class 1 Integron Containing a New Gene Cassette,aadA10, Associated with Tn1404from R151Antimicrobial Agents and Chemotherapy, 2002
- Characterisation of two new gene cassettes,aadA5anddfrA17FEMS Microbiology Letters, 2000
- Plasmid pKM101 encodes two nonhomologous antirestriction proteins (ArdA and ArdB) whose expression is controlled by homologous regulatory sequencesJournal of Bacteriology, 1993