Infections in Patients with Leukemia and Lymphoma
- 6 April 2014
- book chapter
- review article
- Published by Springer Science and Business Media LLC in Cancer Treatment and Research
- Vol. 161, 319-349
- https://doi.org/10.1007/978-3-319-04220-6_11
Abstract
Infectious complications remain a significant issue in the care of patients with hematologic malignancies. Inherent immune defects related to the primary disease process are present in patients with disorders such as chronic lymphocytic leukemia, multiple myeloma, hairy cell leukemia, and Hodgkin lymphoma. Therapy-related immunosuppression is also commonplace in these patients. This includes not only treatment-related neutropenia, but also defects in cell-mediated immunity, such as those that occur with purine analog therapy. In this chapter, we will review the pathogenesis of infection in these disorders, as well as the spectrum of infectious complications seen and suggested strategies for the prevention of infection.This publication has 101 references indexed in Scilit:
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