Intravenous Immunoglobulin for the Prevention of Infection in Chronic Lymphocytic Leukemia
- 6 October 1988
- journal article
- clinical trial
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 319 (14), 902-907
- https://doi.org/10.1056/nejm198810063191403
Abstract
In a double-blind study, we randomly assigned 84 patients with chronic lymphocytic leukemia who were judged to be at increased risk of bacterial infection to receive intravenous immunoglobulin G (400 mg per kilogram of body weight) or a placebo every three weeks for one year. Eligible patients had hypogammaglobulinemia, a history of infection, or both.Keywords
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