An automated modular assembly line for drugs in a miniaturized plant

Abstract

We report here a fully automated, end-to-end, integrated continuous manufacturing process for a small-molecule generic medication with built-in quality assurance. The entire process fits into a box of 30.7 m(2) modular footprint and a total residence time of less than 30 h, with a throughput up to 40.3 x 10(6) tablets per year.