The epidemiology of knee osteoarthritis: Results from the framingham osteoarthritis study
Open Access
- 1 December 1990
- journal article
- Published by Elsevier BV in Seminars in Arthritis and Rheumatism
- Vol. 20 (3), 42-50
- https://doi.org/10.1016/0049-0172(90)90046-i
Abstract
The Framingham Knee Osteoarthritis study is a population-based study of independently living elderly examining the prevalence of radiographic and symptomatic knee osteoarthritis. This group was assessed in the early 1980s at which time they had been observed for over 35 years and many risk factors for osteoarthritis had been ascertained. Results from this study suggest that knee osteoarthritis increases in prevalence throughout the elderly years, more so in women than in men. Also, studies of risk factors have shown that obesity precedes and increases the risk of knee osteoarthritis, especially in women. Other risk factors documented by the Framingham Osteoarthritis study to be important as risk factors for disease include knee injury, chondrocalcinosis, and occupational knee bending and physical labor. Radiographic knee osteoarthritis was negatively associated with smoking. No clearcut relationship of osteoarthritis with estrogen use in women was found. In terms of disability, lower extremity dysfunction is common in patients with knee osteoarthritis, but upper extremity dysfunction is not, and symptoms and severe degrees of radiographic osteoarthritis are associated with higher risks of dysfunction.Keywords
This publication has 10 references indexed in Scilit:
- Defining arthritis and measuring functional status in elders: methodological issues in the study of disease and physical disability.American Journal of Public Health, 1990
- Estrogen use and radiographic osteoarthritis of the knee in womenArthritis & Rheumatism, 1990
- Does smoking protect against osteoarthritis?Arthritis & Rheumatism, 1989
- FACTORS ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE IN THE FIRST NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY (HANES I)American Journal of Epidemiology, 1988
- Obesity and Knee OsteoarthritisAnnals of Internal Medicine, 1988
- Hip Fracture and the Use of Estrogens in Postmenopausal WomenNew England Journal of Medicine, 1987
- The prevalence of knee osteoarthritis in the elderly. the framingham osteoarthritis studyArthritis & Rheumatism, 1987
- Estrogens and OsteoarthritisClinical Orthopaedics and Related Research, 1986
- Role of Subchondral Bone in the Initiation and Progression of Cartilage DamageClinical Orthopaedics and Related Research, 1986
- Osteo-arthrosis and Disk Degeneration in an Urban PopulationAnnals Of The Rheumatic Diseases, 1958