EFFECTS OF CHRONIC EXCESS SALT INGESTION
Open Access
- 1 June 1962
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 115 (6), 1173-1190
- https://doi.org/10.1084/jem.115.6.1173
Abstract
Using the genetic technique of selective inbreeding, it has been possible to quickly develop two statistically separable populations from one unselected strain of Sprague-Dawley rats. One of these is very sensitive, the other very resistant, to the development of experimental hypertension from a high salt diet. It was suggested that similar genetic factors operate in man.Keywords
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