Signal amplification of streptavidin–horseradish peroxidase functionalized carbon nanotubes for amperometric detection of attomolar DNA

Abstract

A novel biosensing strategy for selective electrochemical detection of DNA down to the attomolar level with a linear range of 5 orders of magnitude was developed by the specific recognitions of target DNA and streptavidin to biotin labelled molecular beacon and signal amplification of streptavidin–horseradish peroxidase functionalized carbon nanotubes.