Colloid solutions: a clinical update
- 17 October 2010
- journal article
- review article
- Published by Springer Science and Business Media LLC in Journal of Anesthesia
- Vol. 24 (6), 913-925
- https://doi.org/10.1007/s00540-010-1034-y
Abstract
Albumin, dextran, gelatin, and hydroxyethyl starch (HES) solutions are colloids that efficiently expand the circulating blood volume. The administration of colloids restores the intravascular volume with minimal risk of tissue edema in comparison with crystalloid solutions alone. However, colloids are always given for surgical and critically ill patients. The type of the colloid, volumes applied, aggressiveness of fluid resuscitation, and the volume status at the initial phase of administration determine their clinical responses. The outcome after fluid resuscitation with various colloids in critically ill patients seems to be comparable according to systematic reviews. A randomized, adequately powered clinical trial comparing modern nonprotein colloid to albumin is still lacking. Rapidly degradable HES solutions have good hemodynamic effects, and the risk of adverse renal and coagulation effects, as well as allergic reactions, is minimal. The current investigation has also shown the beneficial effect of HES solution (especially HES 130/0.4) on inflammatory response, postoperative nausea and vomiting, and postoperative outcome. The indication of colloids with an assessment of the degree of hypovolemia and safety profiles should thus be taken into consideration before colloid administration.Keywords
This publication has 138 references indexed in Scilit:
- Hydroxyethyl StarchesAnesthesiology, 2009
- Safety of HES 130/0.4 (Voluven®) in patients with preoperative renal dysfunction undergoing abdominal aortic surgeryEuropean Journal of Anaesthesiology, 2008
- Hemodynamic effects of 6% and 10% hydroxyethyl starch solutions versus 4% albumin solution in septic patientsJournal of Clinical Anesthesia, 2008
- A Rational Approach to Perioperative Fluid ManagementAnesthesiology, 2008
- Pharmacokinetics of Hydroxyethyl StarchClinical Pharmacokinetics, 2005
- Hydroxyethyl starch does not impair immediate renal function in kidney transplant recipients: a retrospective, multicentre analysisNephrology Dialysis Transplantation, 1999
- Hypertonic saline dextran: efficacy and regulatory approvalActa Anaesthesiologica Scandinavica, 1998
- Safety of Dextran in Relation to Other Colloids – Ten Years Experience with Hapten InhibitionTransfusion Medicine and Hemotherapy, 1993
- A narrow range, medium molecular weight pentastarch reduces structural organ damage in a hyperdynamic porcine model of sepsisIntensive Care Medicine, 1992
- Effect of intraoperative fluid administration and colloid osmotic pressure on the formation of intestinal edema during gastrointestinal surgeryJournal of Clinical Anesthesia, 1990