Rapid increase of mitochondrial uncoupling protein and its mRNA in stimulated brown adipose tissue
- 10 December 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 178 (2), 240-244
- https://doi.org/10.1016/0014-5793(84)80608-0
Abstract
The increase in mitochondrial uncoupling protein in brown adipose tissue during acute stimulation by exposure of animals to cold was examined. Uncoupling protein level increased during the first hours of tissue stimulation. Use of a cDNA probe shows that synthesis of uncoupling protein mRNA was quickly stimulated. Animals treated with propranolol exhibited neither increase in uncoupling protein mRNA nor increase in the protein itself.Keywords
This publication has 17 references indexed in Scilit:
- Prolonged β-adrenoceptor stimulation increases the amount of GDP-binding protein in brown adipose tissue mitochondriaLife Sciences, 1984
- Noradrenaline controls the concentration of the uncoupling protein in brown adipose tissueFEBS Letters, 1984
- The regulation of the proton conductance of brown fat mitochondriaFEBS Letters, 1983
- Brown Fat: An Energy Dissipating TissuePublished by Springer Science and Business Media LLC ,1983
- Measurement of rat brown-adipose-tissue mitochondrial uncoupling protein by radioimmunoassay: Increased concentration after cold acclimationBioscience Reports, 1983
- Isolation of the GDP binding protein from brown adipose tissue mitochondria of several animals and amino acid composition study in ratBiochemical and Biophysical Research Communications, 1982
- Polypeptide turnover in brown adipose tissue mitochondria during acclimation of rats to coldCanadian Journal of Biochemistry, 1980
- Brown adipose tissue mitochondriaBiochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics, 1979
- Roles of noradrenaline and protein synthesis in the cold-induced increase in purine nucleotide binding by rat brown adipose tissue mitochondriaCanadian Journal of Biochemistry, 1979
- Mitochondrial protein alteration in active brown fat: A sodium dodecyl sulfate-polyacrylamide gel electrophoretic studyBiochemical and Biophysical Research Communications, 1976