Diastereoselective Silver-Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides with Fluorinated Imine
- 11 October 2010
- journal article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 75 (21), 7468-7471
- https://doi.org/10.1021/jo101447n
Abstract
We described hereby an instance of diastereoselective silver-catalyzed 1,3-dipolar cycloaddition of azomethine ylides with imine compounds. This new method provided synthetically useful, highly substituted tetrahydroimidazole derivatives with efficiency and high diastereoselectivity. We can conveniently obtain fluorinated dihydroimidazole, imidazole, and diamino esters through simple modification.Keywords
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