Simultaneous determination of a hydrophobic drug candidate and its metabolite in human plasma with salting-out assisted liquid/liquid extraction using a mass spectrometry friendly salt
- 1 December 2008
- journal article
- research article
- Published by Elsevier BV in Journal of Pharmaceutical and Biomedical Analysis
- Vol. 48 (4), 1243-1248
- https://doi.org/10.1016/j.jpba.2008.09.002
Abstract
No abstract availableKeywords
This publication has 9 references indexed in Scilit:
- Salting‐out assisted liquid/liquid extraction with acetonitrile: a new high throughput sample preparation technique for good laboratory practice bioanalysis using liquid chromatography–mass spectrometryBiomedical Chromatography, 2008
- Determination of γ-hydroxybutyrate (GHB) and its precursors in blood and urine samples: A salting-out approachForensic Science International, 2007
- Historical review of sample preparation for chromatographic bioanalysis: pros and consDrug Development Research, 2007
- Coupling of acetonitrile deproteinization and salting-out extraction with acetonitrile stacking for biological sample clean-up and the enrichment of hydrophobic compounds (porphyrins) in capillary electrophoresisElectrophoresis, 2006
- A high‐throughput, fully automated liquid/liquid extraction liquid chromatography/mass spectrometry method for the quantitation of a new investigational drug ABT‐869 and its metabolite A‐849529 in human plasma samplesRapid Communications in Mass Spectrometry, 2006
- Polyurethane foam chips combined with liquid chromatography in the determination of unmetabolized polycyclic aromatic hydrocarbons excreted in human urineBiomedical Chromatography, 2006
- Extraction of Thiamylal in Serum Using Hydrophilic Acetonitrile with Subzero-Temperature and Salting-Out MethodsAnalytical Chemistry, 2004
- Chemical Properties of Water-Miscible Solvents Separated by Salting-out and Their Application to Solvent ExtractionAnalytical Sciences, 1994
- Determination of diltiazem in human whole blood and plasma by high-performance liquid chromatography using a polymeric reversed-phase column and utilizing a salting-out extraction procedureJournal of Chromatography B: Biomedical Sciences and Applications, 1989